Table 1 Coverage of labeled structures, number of predicted affinities for unlabeled structures, as well as sensitivity, specificity, precision, and accuracy for HPC-based prediction of binding affinity
From: Structure-guided selection of specificity determining positions in the human Kinome
Strategy | Cov. | #pred. | Sens. | Spec. | Prec. | Acc. |
|---|---|---|---|---|---|---|
1 | 83 % | 215 | 0.486 | 1.000 | 0.921 | 0.904 |
2 | 83 % | 520 | 1.000 | 0.887 | 0.783 | 0.929 |
3 | 15 % | 1,084 | 0.617 | 1.000 | 0.921 | 0.932 |
4 | 71 % | 364 | 1.000 | 0.900 | 0.806 | 0.937 |